Disordered Expression of shaggy, the Drosophila Gene Encoding a Serine-Threonine Protein Kinase GSK3, Affects the Lifespan in a Transcript-, Stage-, and Tissue-Specific Manner

GSK3 (glycogen synthase kinase 3) is a conserved protein kinase governing numerous regulatory pathways. In Drosophila melanogaster, GSK3 is encoded by shaggy (sgg), which forms 17 annotated transcripts corresponding to 10 protein isoforms. Our goal was to demonstrate how differential sgg transcripti...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Trostnikov, Mikhail V., Roshina, Natalia V., Boldyrev, Stepan V., Veselkina, Ekaterina R., Zhuikov, Andrey A., Krementsova, Anna V., Pasyukova, Elena G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540023/
https://ncbi.nlm.nih.gov/pubmed/31060255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092200
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