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Disordered Expression of shaggy, the Drosophila Gene Encoding a Serine-Threonine Protein Kinase GSK3, Affects the Lifespan in a Transcript-, Stage-, and Tissue-Specific Manner

GSK3 (glycogen synthase kinase 3) is a conserved protein kinase governing numerous regulatory pathways. In Drosophila melanogaster, GSK3 is encoded by shaggy (sgg), which forms 17 annotated transcripts corresponding to 10 protein isoforms. Our goal was to demonstrate how differential sgg transcripti...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Trostnikov, Mikhail V., Roshina, Natalia V., Boldyrev, Stepan V., Veselkina, Ekaterina R., Zhuikov, Andrey A., Krementsova, Anna V., Pasyukova, Elena G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540023/
https://ncbi.nlm.nih.gov/pubmed/31060255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092200
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