Disordered Expression of shaggy, the Drosophila Gene Encoding a Serine-Threonine Protein Kinase GSK3, Affects the Lifespan in a Transcript-, Stage-, and Tissue-Specific Manner

GSK3 (glycogen synthase kinase 3) is a conserved protein kinase governing numerous regulatory pathways. In Drosophila melanogaster, GSK3 is encoded by shaggy (sgg), which forms 17 annotated transcripts corresponding to 10 protein isoforms. Our goal was to demonstrate how differential sgg transcripti...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Trostnikov, Mikhail V., Roshina, Natalia V., Boldyrev, Stepan V., Veselkina, Ekaterina R., Zhuikov, Andrey A., Krementsova, Anna V., Pasyukova, Elena G.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540023/
https://ncbi.nlm.nih.gov/pubmed/31060255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092200
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