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Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model

The goal of this study was to investigate Cannabidiol (CBD) hepatotoxicity in 8-week-old male B6C3F(1) mice. Animals were gavaged with either 0, 246, 738, or 2460 mg/kg of CBD (acute toxicity, 24 h) or with daily doses of 0, 61.5, 184.5, or 615 mg/kg for 10 days (sub-acute toxicity). These doses wer...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Ewing, Laura E., Skinner, Charles M., Quick, Charles M., Kennon-McGill, Stefanie, McGill, Mitchell R., Walker, Larry A., ElSohly, Mahmoud A., Gurley, Bill J., Koturbash, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539990/
https://ncbi.nlm.nih.gov/pubmed/31052254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24091694
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