Evolutionary Plasticity in Detoxification Gene Modules: The Preservation and Loss of the Pregnane X Receptor in Chondrichthyes Lineages

To appraise how evolutionary processes, such as gene duplication and loss, influence an organism’s xenobiotic sensitivity is a critical question in toxicology. Of particular importance are gene families involved in the mediation of detoxification responses, such as members of the nuclear receptor su...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Fonseca, Elza S. S., Ruivo, Raquel, Machado, André M., Conrado, Francisca, Tay, Boon-Hui, Venkatesh, Byrappa, Santos, Miguel M., Castro, L. Filipe C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539745/
https://ncbi.nlm.nih.gov/pubmed/31083458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092331
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