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CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy

Activation of multiple pathways is associated with cardiac hypertrophy and heart failure. We previously published that CXCR4 negatively regulates β-adrenergic receptor (β-AR) signaling and ultimately limits β-adrenergic diastolic (Ca(2+)) accumulation in cardiac myocytes. In isolated adult rat cardi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: LaRocca, Thomas J., Altman, Perry, Jarrah, Andrew A., Gordon, Ron, Wang, Edward, Hadri, Lahouaria, Burke, Mark W., Haddad, Georges E., Hajjar, Roger J., Tarzami, Sima T.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539363/
https://ncbi.nlm.nih.gov/pubmed/31071921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092267
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