CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response

CXCR4 and CXCR7 are prominent G protein-coupled receptors (GPCRs) for chemokine stromal cell-derived factor-1 (SDF-1/CXCL12). This study demonstrates that CXCR4 and CXCR7 induce differential effects during cardiac lineage differentiation and β-adrenergic response in human induced pluripotent stem ce...

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Detalhes bibliográficos
Publicado no:Stem Cell Res
Main Authors: Ceholski, Delaine K., Turnbull, Irene C., Pothula, Venu, Lecce, Laura, Jarrah, Andrew A., Kho, Changwon, Lee, Ahyoung, Hadri, Lahouaria, Costa, Kevin D., Hajjar, Roger J., Tarzami, Sima T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859259/
https://ncbi.nlm.nih.gov/pubmed/28711757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2017.06.015
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