Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis

A short form of cellular FLICE-inhibitory protein encoded by CFLARs promotes necroptosis. Although necroptosis is involved in various pathological conditions, the detailed mechanisms are not fully understood. Here we generated transgenic mice wherein CFLARs was integrated onto the X chromosome. All...

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Publicat a:iScience
Autors principals: Shindo, Ryodai, Ohmuraya, Masaki, Komazawa-Sakon, Sachiko, Miyake, Sanae, Deguchi, Yutaka, Yamazaki, Soh, Nishina, Takashi, Yoshimoto, Takayuki, Kakuta, Soichiro, Koike, Masato, Uchiyama, Yasuo, Konishi, Hiroyuki, Kiyama, Hiroshi, Mikami, Tetuo, Moriwaki, Kenta, Araki, Kimi, Nakano, Hiroyasu
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538961/
https://ncbi.nlm.nih.gov/pubmed/31132747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.05.011
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