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Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis

A short form of cellular FLICE-inhibitory protein encoded by CFLARs promotes necroptosis. Although necroptosis is involved in various pathological conditions, the detailed mechanisms are not fully understood. Here we generated transgenic mice wherein CFLARs was integrated onto the X chromosome. All...

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Bibliografische gegevens
Gepubliceerd in:iScience
Hoofdauteurs: Shindo, Ryodai, Ohmuraya, Masaki, Komazawa-Sakon, Sachiko, Miyake, Sanae, Deguchi, Yutaka, Yamazaki, Soh, Nishina, Takashi, Yoshimoto, Takayuki, Kakuta, Soichiro, Koike, Masato, Uchiyama, Yasuo, Konishi, Hiroyuki, Kiyama, Hiroshi, Mikami, Tetuo, Moriwaki, Kenta, Araki, Kimi, Nakano, Hiroyasu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538961/
https://ncbi.nlm.nih.gov/pubmed/31132747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.05.011
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