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Wnt Signaling Deregulation in the Aging and Alzheimer’s Brain

Growing evidence suggests that synaptic signaling is compromised in the aging brain and in Alzheimer’s disease (AD), contributing to synaptic decline. Wnt signaling is a prominent pathway at the synapse and is required for synaptic plasticity and maintenance in the adult brain. In this review, we su...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Palomer, Ernest, Buechler, Johanna, Salinas, Patricia C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538920/
https://ncbi.nlm.nih.gov/pubmed/31191253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00227
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