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Cannabidiol Affects the Bezold-Jarisch Reflex via TRPV1 and 5-HT(3) Receptors and Has Peripheral Sympathomimetic Effects in Spontaneously Hypertensive and Normotensive Rats
Cannabidiol (CBD) is a nonpsychotropic constituent of Cannabis sativa L. It is suggested to be useful in hypertension. Under in vitro conditions, it activates vanilloid TRPV1 and inhibits serotonin 5-HT(3) receptors, i.e., receptors involved in the Bezold-Jarisch reflex stimulation. The aim of our s...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6538767/ https://ncbi.nlm.nih.gov/pubmed/31178718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00500 |
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