Establishment and Characterization of a New Cell Line Permissive for Hepatitis C Virus Infection

Hepatitis C virus (HCV) cell culture systems have facilitated the development of efficient direct-acting antivirals against HCV. Huh-7.5, a subline of the human hepatoma cell line Huh-7, has been used widely to amplify HCV because HCV can efficiently replicate in these cells due to a defect in innat...

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Udgivet i:Sci Rep
Main Authors: Omura, Hitoshi, Liu, Fanwei, Shimakami, Tetsuro, Murai, Kazuhisa, Shirasaki, Takayoshi, Kitabayashi, Juria, Funaki, Masaya, Nishikawa, Tomoki, Nakai, Ryotaro, Sumiyadorj, Ariunaa, Hayashi, Takehiro, Yamashita, Taro, Honda, Masao, Kaneko, Shuichi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538753/
https://ncbi.nlm.nih.gov/pubmed/31138826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44257-5
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