Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques

Tuberculosis (TB) is the leading cause of death from infection worldwide. The only approved vaccine, BCG, has variable protective efficacy against pulmonary TB, the transmissible form of the disease. Therefore, improving this efficacy is an urgent priority. This study assessed whether heterologous p...

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Dades bibliogràfiques
Publicat a:NPJ Vaccines
Autors principals: Darrah, Patricia A., DiFazio, Robert M., Maiello, Pauline, Gideon, Hannah P., Myers, Amy J., Rodgers, Mark A., Hackney, Joshua A., Lindenstrom, Thomas, Evans, Thomas, Scanga, Charles A., Prikhodko, Victor, Andersen, Peter, Lin, Philana Ling, Laddy, Dominick, Roederer, Mario, Seder, Robert A., Flynn, JoAnne L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538611/
https://ncbi.nlm.nih.gov/pubmed/31149352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-019-0113-9
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