Oxidative hotspots on actin promote skeletal muscle weakness in rheumatoid arthritis

Skeletal muscle weakness in patients suffering from rheumatoid arthritis (RA) adds to their impaired working abilities and reduced quality of life. However, little molecular insight is available on muscle weakness associated with RA. Oxidative stress has been implicated in the disease pathogenesis o...

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Publicado en:JCI Insight
Autores principales: Steinz, Maarten M., Persson, Malin, Aresh, Bejan, Olsson, Karl, Cheng, Arthur J., Ahlstrand, Emma, Lilja, Mats, Lundberg, Tommy R., Rullman, Eric, Möller, Kristina Ängeby, Sandor, Katalin, Ajeganova, Sofia, Yamada, Takashi, Beard, Nicole, Karlsson, Björn C.G., Tavi, Pasi, Kenne, Ellinor, Svensson, Camilla I., Rassier, Dilson E., Karlsson, Roger, Friedman, Ran, Gustafsson, Thomas, Lanner, Johanna T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538353/
https://ncbi.nlm.nih.gov/pubmed/30920392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126347
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