Oxidative hotspots on actin promote skeletal muscle weakness in rheumatoid arthritis

Skeletal muscle weakness in patients suffering from rheumatoid arthritis (RA) adds to their impaired working abilities and reduced quality of life. However, little molecular insight is available on muscle weakness associated with RA. Oxidative stress has been implicated in the disease pathogenesis o...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Steinz, Maarten M., Persson, Malin, Aresh, Bejan, Olsson, Karl, Cheng, Arthur J., Ahlstrand, Emma, Lilja, Mats, Lundberg, Tommy R., Rullman, Eric, Möller, Kristina Ängeby, Sandor, Katalin, Ajeganova, Sofia, Yamada, Takashi, Beard, Nicole, Karlsson, Björn C.G., Tavi, Pasi, Kenne, Ellinor, Svensson, Camilla I., Rassier, Dilson E., Karlsson, Roger, Friedman, Ran, Gustafsson, Thomas, Lanner, Johanna T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538353/
https://ncbi.nlm.nih.gov/pubmed/30920392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126347
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