Th1 Biased Progressive Autoimmunity in Aged Aire-Deficient Mice Accelerated Thymic Epithelial Cell Senescence

Although autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, are frequently associated with premature aging of the thymus, a direct link is missing between autoimmunity and thymic atrophy. Here we monitored the progression of thymic involution in Aire-deficient mice,...

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Bibliografiske detaljer
Udgivet i:Aging Dis
Main Authors: Zhang, Jie, Wang, Yuqing, Aili, Abudureyimujiang, Sun, Xiuyuan, Pang, Xuewen, Ge, Qing, Zhang, Yu, Jin, Rong
Format: Artigo
Sprog:Inglês
Udgivet: JKL International LLC 2019
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Orginal Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538216/
https://ncbi.nlm.nih.gov/pubmed/31164995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2018.0608
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