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Mosaic APP Gene Recombination in Alzheimer’s Disease—What’s Next?

A first example of somatic gene recombination (SGR) within the human brain was recently reported, involving the well-known Alzheimer’s disease (AD)-related gene amyloid precursor protein (APP). SGR was characterized by the creation of APP genomic complementary DNA (gencDNA) sequences that were ident...

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Detalhes bibliográficos
Publicado no:J Exp Neurosci
Main Authors: Lee, Ming-Hsiang, Chun, Jerold
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537494/
https://ncbi.nlm.nih.gov/pubmed/31205422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1179069519849669
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