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An image-based assay to quantify changes in proliferation and viability upon drug treatment in 3D microenvironments
BACKGROUND: Every biological experiment requires a choice of throughput balanced against physiological relevance. Most primary drug screens neglect critical parameters such as microenvironmental conditions, cell-cell heterogeneity, and specific readouts of cell fate for the sake of throughput. METHO...
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| Опубликовано в: : | BMC Cancer |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6537405/ https://ncbi.nlm.nih.gov/pubmed/31138163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5694-1 |
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