Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation

Intrauterine hypoxia (IUH) is a common intrauterine dysplasia that can cause programming of the offspring cardiovascular system. In this study, we hypothesized that placental treatment with spermidine (SPD) can prevent heart injury in neonatal offspring exposed to IUH. Pregnant rats were exposed to...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Chai, Nannan, Zhang, Hao, Li, Lingxu, Yu, Xue, Liu, Yan, Lin, Yan, Wang, Lina, Yan, Jiamin, Nikolaevna, Sazonova Elena, Zhao, Yajun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537013/
https://ncbi.nlm.nih.gov/pubmed/31217839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5406468
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