Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation

Intrauterine hypoxia (IUH) is a common intrauterine dysplasia that can cause programming of the offspring cardiovascular system. In this study, we hypothesized that placental treatment with spermidine (SPD) can prevent heart injury in neonatal offspring exposed to IUH. Pregnant rats were exposed to...

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Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Chai, Nannan, Zhang, Hao, Li, Lingxu, Yu, Xue, Liu, Yan, Lin, Yan, Wang, Lina, Yan, Jiamin, Nikolaevna, Sazonova Elena, Zhao, Yajun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537013/
https://ncbi.nlm.nih.gov/pubmed/31217839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5406468
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