Rosiglitazone Improves Glucocorticoid Resistance in a Sudden Sensorineural Hearing Loss by Promoting MAP Kinase Phosphatase-1 Expression

In this study, we investigated the role of MAP kinase phosphatase-1 (MKP-1) and rosiglitazone (RSG) in glucocorticoid resistance and glucocorticoid sensitivity, respectively, using a guinea pig model of lipopolysaccharide- (LPS-) induced sudden sensorineural hearing loss (SSHL). The pigs were divide...

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Bibliografiske detaljer
Udgivet i:Mediators Inflamm
Main Authors: Xia, Liang, Liu, Jingjing, Sun, Yuanyuan, Shi, Haibo, Yang, Guang, Feng, Yanmei, Yin, Shankai
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537012/
https://ncbi.nlm.nih.gov/pubmed/31217747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7915730
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