Rosiglitazone Improves Glucocorticoid Resistance in a Sudden Sensorineural Hearing Loss by Promoting MAP Kinase Phosphatase-1 Expression

In this study, we investigated the role of MAP kinase phosphatase-1 (MKP-1) and rosiglitazone (RSG) in glucocorticoid resistance and glucocorticoid sensitivity, respectively, using a guinea pig model of lipopolysaccharide- (LPS-) induced sudden sensorineural hearing loss (SSHL). The pigs were divide...

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Опубликовано в: :Mediators Inflamm
Главные авторы: Xia, Liang, Liu, Jingjing, Sun, Yuanyuan, Shi, Haibo, Yang, Guang, Feng, Yanmei, Yin, Shankai
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537012/
https://ncbi.nlm.nih.gov/pubmed/31217747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7915730
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