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Zinc cooperates with p53 to inhibit the activity of mitochondrial aconitase through reactive oxygen species accumulation

Metabolic reprogramming is a central hallmark of cancer. Therefore, targeting metabolism may provide an effective strategy for identifying promising drug targets for cancer treatment. In prostate cancer, cells undergo metabolic transformation from zinc‐accumulating, citrate‐producing cells to citrat...

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Bibliografische gegevens
Gepubliceerd in:Cancer Med
Hoofdauteurs: Xue, Ya‐Nan, Liu, Ya‐Nan, Su, Jing, Li, Jiu‐Ling, Wu, Yao, Guo, Rui, Yu, Bing‐Bing, Yan, Xiao‐Yu, Zhang, Li‐Chao, Sun, Lian‐Kun, Li, Yang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536939/
https://ncbi.nlm.nih.gov/pubmed/30972978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2130
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