Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis

Variability in bacterial sterilization is a key feature of Mycobacterium tuberculosis (Mtb) disease. In a population of human macrophages, there are macrophages that restrict Mtb growth and those that do not. However, the sources of heterogeneity in macrophage state during Mtb infection are poorly u...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Bryson, Bryan D., Rosebrock, Tracy R., Tafesse, Fikadu G., Itoh, Christopher Y., Nibasumba, Armel, Babunovic, Gregory H., Corleis, Bjorn, Martin, Constance, Keegan, Caroline, Andrade, Priscila, Realegeno, Susan, Kwon, Douglas, Modlin, Robert L., Fortune, Sarah M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536549/
https://ncbi.nlm.nih.gov/pubmed/31133636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10065-8
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