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Association between APOE4 and biomarkers in cerebral adrenoleukodystrophy

Cerebral adrenoleukodystrophy (cALD) is an inflammatory neurodegenerative disease associated with mutation of the ABCD1 gene. Proteomic analysis of cerebral spinal fluid (CSF) from young males with active cALD revealed markers of inflammation including APOE4. APOE4 genotype has been associated with...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Orchard, Paul J., Markowski, Todd W., Higgins, LeeAnn, Raymond, Gerald V., Nascene, David R., Miller, Weston P., Pierpont, Elizabeth I., Lund, Troy C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536544/
https://ncbi.nlm.nih.gov/pubmed/31133696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44140-3
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