Simultaneous Coinfection of Macaques with Zika and Dengue Viruses Does not Enhance Acute Plasma Viremia but Leads to Activation of Monocyte Subsets and Biphasic Release of Pro-inflammatory Cytokines

The consequences of simultaneous infection with Zika (ZIKV) and Dengue (DENV) viruses are poorly understood. Here we show that rhesus macaques experimentally coinfected simultaneously with ZIKV and DENV-2 demonstrated ZIKV or DENV replication without an enhancement of either infection. Coinfection w...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Valiant, William G., Mattapallil, Mary J., Higgs, Stephen, Huang, Yan-Jang S., Vanlandingham, Dana L., Lewis, Mark G., Mattapallil, Joseph J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536518/
https://ncbi.nlm.nih.gov/pubmed/31133721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44323-y
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