Prior Exposure to Zika Virus Significantly Enhances Peak Dengue-2 Viremia in Rhesus Macaques

Structural and functional homologies between the Zika and Dengue viruses’ envelope proteins raise the possibility that cross-reactive antibodies induced following Zika virus infection might enhance subsequent Dengue infection. Using the rhesus macaque model we show that prior infection with Zika vir...

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Publicado en:Sci Rep
Main Authors: George, Jeffy, Valiant, William G., Mattapallil, Mary J., Walker, Michelle, Huang, Yan-Jang S., Vanlandingham, Dana L., Misamore, John, Greenhouse, Jack, Weiss, Deborah E., Verthelyi, Daniela, Higgs, Stephen, Andersen, Hanne, Lewis, Mark G., Mattapallil, Joseph J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585353/
https://ncbi.nlm.nih.gov/pubmed/28874759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10901-1
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