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Assigning the Absolute Configurations of Chiral Primary Amines Based on Experimental and DFT-Calculated (19)F Nuclear Magnetic Resonance

In this work, a novel method for assigning the absolute configuration of a chiral primary amine has been developed based on the experimental and DFT-calculated (19)F NMR chemical shift differences of its derived two fluorinated amides by reacting with two enantiomers of a chiral derivatizing agent F...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Yang, Shiwei, Bian, Guangling, Sa, Rongjian, Song, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536038/
https://ncbi.nlm.nih.gov/pubmed/31165055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00318
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