Olaparib as maintenance treatment for patients with platinum-sensitive relapsed ovarian cancer

Poly (ADP-ribose) polymerase (PARP) inhibitors were developed with the intention of treating patients with homologous recombination repair deficiency (HRD), specifically for patients with tumours that harbour a BRCA mutation (BRCAm). Evidence from clinical trials to date has demonstrated that patien...

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Bibliografiske detaljer
Udgivet i:Ther Adv Med Oncol
Main Authors: Ledermann, Jonathan A., Pujade-Lauraine, Eric
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2019
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535754/
https://ncbi.nlm.nih.gov/pubmed/31205507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835919849753
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