Quality of life during olaparib maintenance therapy in platinum-sensitive relapsed serous ovarian cancer

BACKGROUND: Maintenance monotherapy with the poly(ADP-ribose) polymerase inhibitor olaparib significantly prolongs progression-free survival over placebo in patients with platinum-sensitive relapsed serous ovarian cancer, with greatest benefit seen in patients with a BRCA1/2 mutation (BRCAm). Preser...

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Dettagli Bibliografici
Pubblicato in:Br J Cancer
Autori principali: Ledermann, Jonathan A, Harter, Philipp, Gourley, Charlie, Friedlander, Michael, Vergote, Ignace, Rustin, Gordon, Scott, Clare, Meier, Werner, Shapira-Frommer, Ronnie, Safra, Tamar, Matei, Daniela, Fielding, Anitra, Bennett, Bryan, Parry, David, Spencer, Stuart, Mann, Helen, Matulonis, Ursula
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129820/
https://ncbi.nlm.nih.gov/pubmed/27824811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.348
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