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Tofacitinib in the treatment of ulcerative colitis: efficacy and safety from clinical trials to real-world experience

Tofacitinib is an oral small molecule directed against the JAK/STAT pathway, blocking the inflammatory cascade. Oral formulation of tofacitinib has recently been approved for the treatment of patients with moderate–severe ulcerative colitis. Its efficacy and safety have been demonstrated in three ph...

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Detalhes bibliográficos
Publicado no:Therap Adv Gastroenterol
Main Authors: D’Amico, Ferdinando, Parigi, Tommaso Lorenzo, Fiorino, Gionata, Peyrin-Biroulet, Laurent, Danese, Silvio
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535722/
https://ncbi.nlm.nih.gov/pubmed/31205486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284819848631
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