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Tofacitinib in the treatment of ulcerative colitis: efficacy and safety from clinical trials to real-world experience

Tofacitinib is an oral small molecule directed against the JAK/STAT pathway, blocking the inflammatory cascade. Oral formulation of tofacitinib has recently been approved for the treatment of patients with moderate–severe ulcerative colitis. Its efficacy and safety have been demonstrated in three ph...

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Detalhes bibliográficos
Main Authors: Ferdinando D’Amico, Tommaso Lorenzo Parigi, Gionata Fiorino, Laurent Peyrin-Biroulet, Silvio Danese
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publishing 2019-05-01
Colecção:Therapeutic Advances in Gastroenterology
Acesso em linha:https://doi.org/10.1177/1756284819848631
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