Population Pharmacokinetics and Dosing Optimization of Imipenem in Children with Hematological Malignancies

Imipenem is widely used for the treatment of children with serious infections. Currently, studies on the pharmacokinetics of imipenem in children with hematological malignancies are lacking. Given the significant impact of disease on pharmacokinetics and increased resistance, we aimed to conduct a p...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Dong, Lei, Zhai, Xiao-Ying, Yang, Yi-Lei, Wang, Li, Zhou, Yue, Shi, Hai-Yan, Tang, Bo-Hao, Wu, Yue-E, Yang, Fan, Wen, Li, Kong, Hong-Xiao, Zhi, Li-Juan, Jacqz-Aigrain, Evelyne, Zhao, Wei
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535524/
https://ncbi.nlm.nih.gov/pubmed/30962334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00006-19
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