Lysocins: Bioengineered Antimicrobials That Deliver Lysins across the Outer Membrane of Gram-Negative Bacteria

The prevalence of multidrug-resistant Pseudomonas aeruginosa has stimulated development of alternative therapeutics. Bacteriophage peptidoglycan hydrolases, termed lysins, represent an emerging antimicrobial option for targeting Gram-positive bacteria. However, lysins against Gram-negatives are gene...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Heselpoth, Ryan D., Euler, Chad W., Schuch, Raymond, Fischetti, Vincent A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535517/
https://ncbi.nlm.nih.gov/pubmed/30962344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00342-19
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