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Mouse Neuroblastoma CB(1) Cannabinoid Receptor-Stimulated [(35)S]GTPɣS Binding: Total and Antibody-Targeted Gα Protein-Specific Scintillation Proximity Assays

G protein-coupled receptors (GPCRs) are important regulators of cellular signaling functions and therefore are a major target for drug discovery. The CB(1) cannabinoid receptor is among the most highly expressed GPCRs in neurons, where it regulates many differentiated neuronal functions. One model s...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Eldeeb, Khalil, Leone-Kabler, Sandra, Howlett, Allyn C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535336/
https://ncbi.nlm.nih.gov/pubmed/28750799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.06.028
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