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Base editing: precision chemistry on the genome and transcriptome of living cells
RNA-guided programmable nucleases from CRISPR systems generate precise breaks in DNA or RNA at specified positions. In cells, this activity can lead to changes in DNA sequence or RNA transcript abundance. Base editing is a newer genome editing approach that uses components from CRISPR systems togeth...
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| Vydáno v: | Nat Rev Genet |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6535181/ https://ncbi.nlm.nih.gov/pubmed/30323312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41576-018-0059-1 |
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