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Calcium-sensing receptor in physiology and in calcitropic and non-calcitropic diseases
The Ca(2+)-sensing receptor (CaSR) is a dimeric family C G-protein-coupled receptor that is expressed in calcitropic tissues such as the parathyroid glands and kidneys, and signals via G-proteins and beta-arrestin. The CaSR plays a pivotal role in bone and mineral metabolism by regulating parathyroi...
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| Publicado en: | Nat Rev Endocrinol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6535143/ https://ncbi.nlm.nih.gov/pubmed/30443043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41574-018-0115-0 |
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