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Calcium-sensing receptor in physiology and in calcitropic and non-calcitropic diseases

The Ca(2+)-sensing receptor (CaSR) is a dimeric family C G-protein-coupled receptor that is expressed in calcitropic tissues such as the parathyroid glands and kidneys, and signals via G-proteins and beta-arrestin. The CaSR plays a pivotal role in bone and mineral metabolism by regulating parathyroi...

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Podrobná bibliografie
Vydáno v:Nat Rev Endocrinol
Hlavní autoři: Hannan, Fadil M., Kallay, Enikö, Chang, Wenhan, Brandi, Maria Luisa, Thakker, Rajesh V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535143/
https://ncbi.nlm.nih.gov/pubmed/30443043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41574-018-0115-0
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