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MiR-124 sensitizes cisplatin-induced cytotoxicity against CD133(+) hepatocellular carcinoma cells by targeting SIRT1/ROS/JNK pathway

Drug resistance is still a major obstacle for efficient treatment of hepatocellular carcinoma (HCC) during the cisplatin-based chemotherapy. Recent studies have demonstrated that CD133 positive population of cancer cells are responsible for multiple drug resistance. We are supposed to take strategie...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Xu, Yunxiuxiu, Lai, Yu, Weng, Hanqin, Tan, Lanping, Li, Yanshan, Chen, Guangcheng, Luo, Xingxi, Ye, Yibiao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535064/
https://ncbi.nlm.nih.gov/pubmed/31056532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101876
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