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Modulation of Coenzyme Q(10) content and oxidative status in human dermal fibroblasts using HMG-CoA reductase inhibitor over a broad range of concentrations. From mitohormesis to mitochondrial dysfunction and accelerated aging

Coenzyme Q(10) (CoQ(10)) is an endogenous lipophilic quinone, ubiquitous in biological membranes and endowed with antioxidant and bioenergetic properties, both crucial to the aging process. In fact, coenzyme Q(10) synthesis is known to decrease with age in different tissues including skin. Moreover,...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Marcheggiani, Fabio, Cirilli, Ilenia, Orlando, Patrick, Silvestri, Sonia, Vogelsang, Alexandra, Knott, Anja, Blatt, Thomas, Weise, Julia M., Tiano, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535058/
https://ncbi.nlm.nih.gov/pubmed/31076563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101926
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