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Modulation of Coenzyme Q(10) content and oxidative status in human dermal fibroblasts using HMG-CoA reductase inhibitor over a broad range of concentrations. From mitohormesis to mitochondrial dysfunction and accelerated aging

Coenzyme Q(10) (CoQ(10)) is an endogenous lipophilic quinone, ubiquitous in biological membranes and endowed with antioxidant and bioenergetic properties, both crucial to the aging process. In fact, coenzyme Q(10) synthesis is known to decrease with age in different tissues including skin. Moreover,...

詳細記述

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書誌詳細
出版年:Aging (Albany NY)
主要な著者: Marcheggiani, Fabio, Cirilli, Ilenia, Orlando, Patrick, Silvestri, Sonia, Vogelsang, Alexandra, Knott, Anja, Blatt, Thomas, Weise, Julia M., Tiano, Luca
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535058/
https://ncbi.nlm.nih.gov/pubmed/31076563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101926
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