Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide

BACKGROUND: Androgen receptor (AR) is expressed in approximately 70% of breast tumors. Recent studies increasingly support AR as a potential therapeutic target of AR-positive breast cancer. We have previously reported that deubiquitinase USP14 stabilizes AR proteins by deubiquitination and USP14 inh...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Xia, Xiaohong, Huang, Chuyi, Liao, Yuning, Liu, Yuan, He, Jinchan, Guo, Zhiqiang, Jiang, Lili, Wang, Xuejun, Liu, Jinbao, Huang, Hongbiao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534920/
https://ncbi.nlm.nih.gov/pubmed/31126320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1227-7
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