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Drug transporter and oxidative stress gene expression in human macrophages infected with benznidazole-sensitive and naturally benznidazole-resistant Trypanosoma cruzi parasites treated with benznidazole

BACKGROUND: Chagas disease is a potentially life-threatening disease caused by the protozoan parasite Trypanosoma cruzi. Current therapeutic management is limited to treatment with nitroheterocyclic drugs, such as nifurtimox (NFX) and benznidazole (BZ). Thus, the identification of affordable and rea...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Parasit Vectors
Egile Nagusiak: Téllez, Jair, Romero, Ibeth, Romanha, Alvaro José, Steindel, Mario
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534881/
https://ncbi.nlm.nih.gov/pubmed/31126349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-019-3485-9
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