1,2,3,4,6‐Penta‐O‐galloyl‐β‐d‐glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II‐induced hypertension

BACKGROUND AND PURPOSE: Hypertension is a multifactorial disease, manifested by vascular dysfunction, increased superoxide production, and perivascular inflammation. In this study, we have hypothesized that 1,2,3,4,6‐penta‐O‐galloyl‐β‐d‐glucose (PGG) would inhibit vascular inflammation and protect f...

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Pubblicato in:Br J Pharmacol
Autori principali: Mikolajczyk, Tomasz P., Nosalski, Ryszard, Skiba, Dominik S., Koziol, Joanna, Mazur, Magdalena, Justo‐Junior, Amauri S., Kowalczyk, Paulina, Kusmierczyk, Zofia, Schramm‐Luc, Agata, Luc, Kevin, Maffia, Pasquale, Graham, Delyth, Kiss, Anna K., Naruszewicz, Marek, Guzik, Tomasz J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Themed Section: Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534792/
https://ncbi.nlm.nih.gov/pubmed/30658013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14583
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