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Pax3 cooperates with Ldb1 to direct local chromosome architecture during myogenic lineage specification

Chromatin looping allows enhancer-bound regulatory factors to influence transcription. Large domains, referred to as topologically associated domains, participate in genome organization. However, the mechanisms underlining interactions within these domains, which control gene expression, are not ful...

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Vydáno v:Nat Commun
Hlavní autoři: Magli, Alessandro, Baik, June, Pota, Pruthvi, Cordero, Carolina Ortiz, Kwak, Il-Youp, Garry, Daniel J., Love, Paul E., Dynlacht, Brian D., Perlingeiro, Rita C. R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534668/
https://ncbi.nlm.nih.gov/pubmed/31127120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10318-6
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