Time-dependent Pax3-mediated chromatin remodeling and cooperation with Six4 and Tead2 specify the skeletal myogenic lineage in developing mesoderm

The transcriptional mechanisms driving lineage specification during development are still largely unknown, as the interplay of multiple transcription factors makes it difficult to dissect these molecular events. Using a cell-based differentiation platform to probe transcription function, we investig...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Magli, Alessandro, Baik, June, Mills, Lauren J., Kwak, Il-Youp, Dillon, Bridget S., Mondragon Gonzalez, Ricardo, Stafford, David A., Swanson, Scott A., Stewart, Ron, Thomson, James A., Garry, Daniel J., Dynlacht, Brian D., Perlingeiro, Rita C. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6390996/
https://ncbi.nlm.nih.gov/pubmed/30807574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000153
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