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Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors

Metastasis underlies the majority of cancer-related deaths yet remains poorly understood due, in part, to the lack of models in vivo. Here we show that expression of the EMT master inducer Snail in primary adult Drosophila intestinal tumors leads to the dissemination of tumor cells and formation of...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Campbell, Kyra, Rossi, Fabrizio, Adams, Jamie, Pitsidianaki, Ioanna, Barriga, Francisco M., Garcia-Gerique, Laura, Batlle, Eduard, Casanova, Jordi, Casali, Andreu
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534551/
https://ncbi.nlm.nih.gov/pubmed/31127094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10269-y
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