Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors

Metastasis underlies the majority of cancer-related deaths yet remains poorly understood due, in part, to the lack of models in vivo. Here we show that expression of the EMT master inducer Snail in primary adult Drosophila intestinal tumors leads to the dissemination of tumor cells and formation of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Campbell, Kyra, Rossi, Fabrizio, Adams, Jamie, Pitsidianaki, Ioanna, Barriga, Francisco M., Garcia-Gerique, Laura, Batlle, Eduard, Casanova, Jordi, Casali, Andreu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534551/
https://ncbi.nlm.nih.gov/pubmed/31127094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10269-y
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