Schistosoma mansoni treatment reduces HIV entry into cervical CD4+ T cells and induces IFN-I pathways

Schistosoma mansoni (Sm) infection has been linked with an increased risk of HIV acquisition in women. Therefore, defining the mechanism(s) by which Sm alters HIV susceptibility might lead to new HIV prevention strategies. Here, we analyze the impact of standard Sm therapy in HIV-uninfected Sm+ Ugan...

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Udgivet i:Nat Commun
Main Authors: Yegorov, Sergey, Joag, Vineet, Galiwango, Ronald M., Good, Sara V., Mpendo, Juliet, Tannich, Egbert, Boggild, Andrea K., Kiwanuka, Noah, Bagaya, Bernard S., Kaul, Rupert
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534541/
https://ncbi.nlm.nih.gov/pubmed/31127086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09900-9
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