Schistosoma mansoni Infection in Ugandan Men Is Associated with Increased Abundance and Function of HIV Target Cells in Blood, but Not the Foreskin: A Cross-sectional Study

BACKGROUND: Schistosoma mansoni infection has been associated with an increased HIV prevalence in humans and SHIV incidence in primate models. We hypothesized that immune activation from this gastrointestinal mucosa infection would increase highly HIV-susceptible CD4 T cell subsets in the blood and...

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Udgivet i:PLoS Negl Trop Dis
Main Authors: Prodger, Jessica L., Ssemaganda, Aloysious, Ssetaala, Ali, Kitandwe, Paul K., Muyanja, Enoch, Mpendo, Juliet, Nanvubya, Annet, Wambuzi, Mathias, Nielsen, Leslie, Kiwanuka, Noah, Kaul, Rupert
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559468/
https://ncbi.nlm.nih.gov/pubmed/26335139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004067
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