Schistosoma mansoni Infection in Ugandan Men Is Associated with Increased Abundance and Function of HIV Target Cells in Blood, but Not the Foreskin: A Cross-sectional Study

BACKGROUND: Schistosoma mansoni infection has been associated with an increased HIV prevalence in humans and SHIV incidence in primate models. We hypothesized that immune activation from this gastrointestinal mucosa infection would increase highly HIV-susceptible CD4 T cell subsets in the blood and...

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Dettagli Bibliografici
Pubblicato in:PLoS Negl Trop Dis
Autori principali: Prodger, Jessica L., Ssemaganda, Aloysious, Ssetaala, Ali, Kitandwe, Paul K., Muyanja, Enoch, Mpendo, Juliet, Nanvubya, Annet, Wambuzi, Mathias, Nielsen, Leslie, Kiwanuka, Noah, Kaul, Rupert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559468/
https://ncbi.nlm.nih.gov/pubmed/26335139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004067
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