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Wnt Signaling Mediates the Aging-Induced Differentiation Impairment of Intestinal Stem Cells
Stem cell aging underlies aging-associated disorders, such as steeply increased incidences of tumors and impaired regeneration capacity upon stress. However, whether and how the intestinal stem cells age remains largely unknown. Here we show that intestinal stem cells derived from 24-month-old mice...
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| Udgivet i: | Stem Cell Rev |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6534527/ https://ncbi.nlm.nih.gov/pubmed/30790135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-019-09880-9 |
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