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Proniosomal gel-derived niosomes: an approach to sustain and improve the ocular delivery of brimonidine tartrate; formulation, in-vitro characterization, and in-vivo pharmacodynamic study

Brimonidine tartrate (BRT) is a hydrophilic α(2) adrenergic agonist used for the treatment of glaucoma. Glaucoma is an ocular disease affecting the anterior segment of the eye requiring lifetime treatment. Owing to the obstacles facing ocular delivery systems and hydrophilicity of BRT, frequent admi...

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Bibliografske podrobnosti
izdano v:Drug Deliv
Main Authors: Emad Eldeeb, Alaa, Salah, Salwa, Ghorab, Mahmoud
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534210/
https://ncbi.nlm.nih.gov/pubmed/31090464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1609622
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